Dissociatives, adulterants and exposure markers

Does a drug test detect Xylazine?

Yes. Xylazine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 10 ng/mL. Xylazine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

10 ng/mLLaboratory cut-off
10–1,000 ng/mLReportable range
LC-MS/MSConfirmation method

What is Xylazine?

Xylazine is a veterinary sedative that is not approved for use in people. It has become a common adulterant in the illicit fentanyl supply, where it is sometimes called 'tranq'.

Also known as or found in: tranq.

Medical use

Xylazine is approved only for veterinary use, mainly as a sedative for large animals.

How LabX tests for Xylazine

Xylazine is measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS), which separates the compounds in a sample and identifies each one by its mass. That is different from a rapid screen, which reacts to a family of drugs and can occasionally react to a related substance. The laboratory reports Xylazine as detected when its concentration is at or above the cut-off of 10 ng/mL, within a reportable range of 10–1,000 ng/mL. It is one of 6 compounds in the dissociatives, adulterants and exposure markers family on the 76-drug confirmation panel.

Detection window

The laboratory's confirmation report does not print a standard detection window for Xylazine. How long any compound stays measurable varies with the amount taken, how often it is used, metabolism and hydration, and a laboratory result cannot be used to work out when a substance was taken.

Screen versus confirmation

Xylazine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

Worth knowing

Xylazine is not detected by standard drug screens and does not respond to naloxone the way opioids do. Laboratory confirmation identifies it, which can matter for a person's medical care.

About this drug family

Dissociative drugs, the street-supply adulterant xylazine, and markers of cannabis and alcohol exposure.

Common questions

Does a drug test detect Xylazine?

Yes. Xylazine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 10 ng/mL. Xylazine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

What is the laboratory cut-off for Xylazine?

LabX reports Xylazine as detected at or above 10 ng/mL, and the method's reportable range is 10–1,000 ng/mL. A result below the cut-off is reported as not detected; it does not prove none was present.

How long can Xylazine be detected?

The laboratory report does not print a standard window for Xylazine. Detection time varies with dose, frequency of use, metabolism and hydration.

Can a 12-panel drug screen detect Xylazine?

Xylazine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

Is Xylazine a prescription medicine?

Xylazine is approved only for veterinary use, mainly as a sedative for large animals.

Related compounds

Terms on this page: metabolite Β· cut-off Β· detection window Β· presumptive result Β· confirmation test. More questions: LabX answers.

Test for Xylazine and 75 other compounds

12-panel urine $89 or fingerstick blood $99, plus the 76-drug LC-MS/MS confirmation for +$89.

At-home drug tests and test kits are not currently available to addresses in New York, New Jersey, Rhode Island or California. Results are not a diagnosis β€” review them with a licensed physician.

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Talk to a licensed physician. LabX Diagnostics and Vantage provide laboratory testing only. The information on this page is educational and is not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about test results, symptoms or medicines, and before making any health decision. If you think you may have a medical emergency, call 911. Read our medical disclaimer.

Medical disclaimer. LabX Diagnostics and Vantage provide laboratory testing only. Test results and information on this site are for informational purposes and are not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about your results and before making any health decision. If you think you may have a medical emergency, call 911. Read the full disclaimer.

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