Yes. O-desmethylvenlafaxine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 50 ng/mL. It is a breakdown product of venlafaxine (Effexor). O-desmethylvenlafaxine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
O-desmethylvenlafaxine is the main active metabolite of venlafaxine. It is also prescribed in its own right as desvenlafaxine.
Also known as or found in: desvenlafaxine, Pristiq.
As desvenlafaxine, it is prescribed for depression.
Because O-desmethylvenlafaxine comes from Venlafaxine, the two are reported side by side and read together.
O-desmethylvenlafaxine is measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS), which separates the compounds in a sample and identifies each one by its mass. That is different from a rapid screen, which reacts to a family of drugs and can occasionally react to a related substance. The laboratory reports O-desmethylvenlafaxine as detected when its concentration is at or above the cut-off of 50 ng/mL, within a reportable range of 50–5,000 ng/mL. It is one of 14 compounds in the antidepressants family on the 76-drug confirmation panel.
The laboratory's confirmation report does not print a standard detection window for O-desmethylvenlafaxine. How long any compound stays measurable varies with the amount taken, how often it is used, metabolism and hydration, and a laboratory result cannot be used to work out when a substance was taken.
O-desmethylvenlafaxine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
Because it can come from venlafaxine or from desvenlafaxine, this result is interpreted alongside the person's prescription history.
Commonly prescribed antidepressants and their metabolites. They are not part of standard drug screens and are identified when a clinician needs a full medication picture.
Yes. O-desmethylvenlafaxine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 50 ng/mL. It is a breakdown product of venlafaxine (Effexor). O-desmethylvenlafaxine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
LabX reports O-desmethylvenlafaxine as detected at or above 50 ng/mL, and the method's reportable range is 50–5,000 ng/mL. A result below the cut-off is reported as not detected; it does not prove none was present.
The laboratory report does not print a standard window for O-desmethylvenlafaxine. Detection time varies with dose, frequency of use, metabolism and hydration.
O-desmethylvenlafaxine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
As desvenlafaxine, it is prescribed for depression.
O-desmethylvenlafaxine is a breakdown product of venlafaxine (Effexor). Laboratories measure it because it shows the parent drug was actually processed by the body.
Terms on this page: metabolite · cut-off · detection window · presumptive result · confirmation test. More questions: LabX answers.
Test for O-desmethylvenlafaxine and 75 other compounds
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