Antidepressants

Does a drug test detect Bupropion?

Yes. Bupropion is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 40 ng/mL. Bupropion is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

40 ng/mLLaboratory cut-off
40–4,000 ng/mLReportable range
LC-MS/MSConfirmation method

What is Bupropion?

Bupropion is an antidepressant that acts mainly on dopamine and norepinephrine. It is chemically different from SSRIs and tricyclic antidepressants.

Also known as or found in: Wellbutrin, Zyban.

Medical use

Bupropion is prescribed for depression, seasonal affective disorder and as an aid to quitting smoking.

How LabX tests for Bupropion

Bupropion is measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS), which separates the compounds in a sample and identifies each one by its mass. That is different from a rapid screen, which reacts to a family of drugs and can occasionally react to a related substance. The laboratory reports Bupropion as detected when its concentration is at or above the cut-off of 40 ng/mL, within a reportable range of 40–4,000 ng/mL. It is one of 14 compounds in the antidepressants family on the 76-drug confirmation panel.

Detection window

The laboratory's confirmation report does not print a standard detection window for Bupropion. How long any compound stays measurable varies with the amount taken, how often it is used, metabolism and hydration, and a laboratory result cannot be used to work out when a substance was taken.

Screen versus confirmation

Bupropion is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

Worth knowing

Bupropion has been reported to cause false-positive amphetamine results on some immunoassay screens. LC-MS/MS confirmation identifies bupropion itself.

About this drug family

Commonly prescribed antidepressants and their metabolites. They are not part of standard drug screens and are identified when a clinician needs a full medication picture.

Common questions

Does a drug test detect Bupropion?

Yes. Bupropion is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 40 ng/mL. Bupropion is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

What is the laboratory cut-off for Bupropion?

LabX reports Bupropion as detected at or above 40 ng/mL, and the method's reportable range is 40–4,000 ng/mL. A result below the cut-off is reported as not detected; it does not prove none was present.

How long can Bupropion be detected?

The laboratory report does not print a standard window for Bupropion. Detection time varies with dose, frequency of use, metabolism and hydration.

Can a 12-panel drug screen detect Bupropion?

Bupropion is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

Is Bupropion a prescription medicine?

Bupropion is prescribed for depression, seasonal affective disorder and as an aid to quitting smoking.

Related compounds

Terms on this page: metabolite Β· cut-off Β· detection window Β· presumptive result Β· confirmation test. More questions: LabX answers.

Test for Bupropion and 75 other compounds

12-panel urine $89 or fingerstick blood $99, plus the 76-drug LC-MS/MS confirmation for +$89.

At-home drug tests and test kits are not currently available to addresses in New York, New Jersey, Rhode Island or California. Results are not a diagnosis β€” review them with a licensed physician.

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Talk to a licensed physician. LabX Diagnostics and Vantage provide laboratory testing only. The information on this page is educational and is not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about test results, symptoms or medicines, and before making any health decision. If you think you may have a medical emergency, call 911. Read our medical disclaimer.

Medical disclaimer. LabX Diagnostics and Vantage provide laboratory testing only. Test results and information on this site are for informational purposes and are not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about your results and before making any health decision. If you think you may have a medical emergency, call 911. Read the full disclaimer.

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