Fentanyl and novel opioids

Does a drug test detect 7-OH-mitragynine?

Yes. 7-OH-mitragynine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 50 ng/mL. It is a breakdown product of mitragynine (kratom). 7-OH-mitragynine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

50 ng/mLLaboratory cut-off
50–5,000 ng/mLReportable range
LC-MS/MSConfirmation method

What is 7-OH-mitragynine?

7-Hydroxymitragynine (7-OH) is a kratom alkaloid that is also formed from mitragynine in the body. It acts on opioid receptors more strongly than mitragynine, and concentrated 7-OH products are sold separately from traditional kratom.

Medical use

7-Hydroxymitragynine is not an FDA-approved medicine, and its regulatory status is under active review.

Because 7-OH-mitragynine comes from Mitragynine, the two are reported side by side and read together.

How LabX tests for 7-OH-mitragynine

7-OH-mitragynine is measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS), which separates the compounds in a sample and identifies each one by its mass. That is different from a rapid screen, which reacts to a family of drugs and can occasionally react to a related substance. The laboratory reports 7-OH-mitragynine as detected when its concentration is at or above the cut-off of 50 ng/mL, within a reportable range of 50–5,000 ng/mL. It is one of 4 compounds in the fentanyl and novel opioids family on the 76-drug confirmation panel.

Detection window

The laboratory's confirmation report does not print a standard detection window for 7-OH-mitragynine. How long any compound stays measurable varies with the amount taken, how often it is used, metabolism and hydration, and a laboratory result cannot be used to work out when a substance was taken.

Screen versus confirmation

7-OH-mitragynine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

Worth knowing

Measuring 7-hydroxymitragynine alongside mitragynine helps a laboratory report reflect both traditional kratom products and concentrated 7-OH products.

About this drug family

Fentanyl and its metabolite, plus the main alkaloids in kratom. These are not reliably found by general opiate screens, which is why confirmation measures them directly.

Common questions

Does a drug test detect 7-OH-mitragynine?

Yes. 7-OH-mitragynine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 50 ng/mL. It is a breakdown product of mitragynine (kratom). 7-OH-mitragynine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

What is the laboratory cut-off for 7-OH-mitragynine?

LabX reports 7-OH-mitragynine as detected at or above 50 ng/mL, and the method's reportable range is 50–5,000 ng/mL. A result below the cut-off is reported as not detected; it does not prove none was present.

How long can 7-OH-mitragynine be detected?

The laboratory report does not print a standard window for 7-OH-mitragynine. Detection time varies with dose, frequency of use, metabolism and hydration.

Can a 12-panel drug screen detect 7-OH-mitragynine?

7-OH-mitragynine is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.

Is 7-OH-mitragynine a prescription medicine?

7-Hydroxymitragynine is not an FDA-approved medicine, and its regulatory status is under active review.

What drug does 7-OH-mitragynine come from?

7-OH-mitragynine is a breakdown product of mitragynine (kratom). Laboratories measure it because it shows the parent drug was actually processed by the body.

Related compounds

Terms on this page: metabolite Β· cut-off Β· detection window Β· presumptive result Β· confirmation test. More questions: LabX answers.

Test for 7-OH-mitragynine and 75 other compounds

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Talk to a licensed physician. LabX Diagnostics and Vantage provide laboratory testing only. The information on this page is educational and is not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about test results, symptoms or medicines, and before making any health decision. If you think you may have a medical emergency, call 911. Read our medical disclaimer.

Medical disclaimer. LabX Diagnostics and Vantage provide laboratory testing only. Test results and information on this site are for informational purposes and are not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about your results and before making any health decision. If you think you may have a medical emergency, call 911. Read the full disclaimer.

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