Stimulants

Does a drug test detect Benzoylecgonine?

Yes. Benzoylecgonine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 20 ng/mL. It is a breakdown product of cocaine. The LabX 12-panel screen includes a Cocaine line designed to pick up Benzoylecgonine. A screen is presumptive; adding laboratory confirmation identifies Benzoylecgonine specifically.

20 ng/mLLaboratory cut-off
20–5,000 ng/mLReportable range
3-5 daysApprox. window (varies)
LC-MS/MSConfirmation method

What is Benzoylecgonine?

Benzoylecgonine is the main metabolite of cocaine. Cocaine itself breaks down quickly, so laboratories test for benzoylecgonine, which lasts longer and is specific to cocaine.

Also known as or found in: cocaine metabolite.

Medical use

Cocaine has a limited medical use as a topical anesthetic in certain nose and throat procedures. Benzoylecgonine itself is not a medicine.

How LabX tests for Benzoylecgonine

Benzoylecgonine is measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS), which separates the compounds in a sample and identifies each one by its mass. That is different from a rapid screen, which reacts to a family of drugs and can occasionally react to a related substance. The laboratory reports Benzoylecgonine as detected when its concentration is at or above the cut-off of 20 ng/mL, within a reportable range of 20–5,000 ng/mL. It is one of 8 compounds in the stimulants family on the 76-drug confirmation panel.

Detection window

The laboratory's confirmation report lists an approximate detection window of 3-5 days for Benzoylecgonine. Treat that as a rough guide only: how long any compound stays measurable varies with the amount taken, how often it is used, body composition, metabolism, kidney and liver function, and hydration. A laboratory result cannot be used to work out when a substance was taken.

Screen versus confirmation

The LabX 12-panel screen includes a Cocaine line designed to pick up Benzoylecgonine. A screen is presumptive; adding laboratory confirmation identifies Benzoylecgonine specifically.

Worth knowing

Because benzoylecgonine is not produced by ordinary medicines, it is one of the more specific compounds on a drug test. A licensed physician can advise if a medical procedure used topical cocaine.

About this drug family

Prescription ADHD and weight-management stimulants, a common decongestant, and illicit stimulants including the cocaine metabolite benzoylecgonine and MDMA.

Common questions

Does a drug test detect Benzoylecgonine?

Yes. Benzoylecgonine is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 20 ng/mL. It is a breakdown product of cocaine. The LabX 12-panel screen includes a Cocaine line designed to pick up Benzoylecgonine. A screen is presumptive; adding laboratory confirmation identifies Benzoylecgonine specifically.

What is the laboratory cut-off for Benzoylecgonine?

LabX reports Benzoylecgonine as detected at or above 20 ng/mL, and the method's reportable range is 20–5,000 ng/mL. A result below the cut-off is reported as not detected; it does not prove none was present.

How long can Benzoylecgonine be detected?

The laboratory lists an approximate window of 3-5 days, but it varies with dose, frequency of use, metabolism and hydration, and cannot be used to tell when something was taken.

Can a 12-panel drug screen detect Benzoylecgonine?

The LabX 12-panel screen includes a Cocaine line designed to pick up Benzoylecgonine. A screen is presumptive; adding laboratory confirmation identifies Benzoylecgonine specifically.

Is Benzoylecgonine a prescription medicine?

Cocaine has a limited medical use as a topical anesthetic in certain nose and throat procedures. Benzoylecgonine itself is not a medicine.

What drug does Benzoylecgonine come from?

Benzoylecgonine is a breakdown product of cocaine. Laboratories measure it because it shows the parent drug was actually processed by the body.

Related compounds

Terms on this page: metabolite Β· cut-off Β· detection window Β· presumptive result Β· confirmation test. More questions: LabX answers.

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Talk to a licensed physician. LabX Diagnostics and Vantage provide laboratory testing only. The information on this page is educational and is not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about test results, symptoms or medicines, and before making any health decision. If you think you may have a medical emergency, call 911. Read our medical disclaimer.

Medical disclaimer. LabX Diagnostics and Vantage provide laboratory testing only. Test results and information on this site are for informational purposes and are not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about your results and before making any health decision. If you think you may have a medical emergency, call 911. Read the full disclaimer.

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