Yes. 9-Hydroxyrisperidone is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 50 ng/mL. It is a breakdown product of risperidone (Risperdal). 9-Hydroxyrisperidone is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
9-Hydroxyrisperidone is the main active metabolite of risperidone. It is also prescribed on its own as paliperidone.
Also known as or found in: paliperidone, Invega.
As paliperidone, it is prescribed for schizophrenia and schizoaffective disorder, including as a long-acting injection.
Because 9-Hydroxyrisperidone comes from Risperidone, the two are reported side by side and read together.
9-Hydroxyrisperidone is measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS), which separates the compounds in a sample and identifies each one by its mass. That is different from a rapid screen, which reacts to a family of drugs and can occasionally react to a related substance. The laboratory reports 9-Hydroxyrisperidone as detected when its concentration is at or above the cut-off of 50 ng/mL, within a reportable range of 50–4,000 ng/mL. It is one of 6 compounds in the antipsychotics and mood family on the 76-drug confirmation panel.
The laboratory's confirmation report lists an approximate detection window of 1-5 days for 9-Hydroxyrisperidone. Treat that as a rough guide only: how long any compound stays measurable varies with the amount taken, how often it is used, body composition, metabolism, kidney and liver function, and hydration. A laboratory result cannot be used to work out when a substance was taken.
9-Hydroxyrisperidone is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
This result can reflect risperidone or paliperidone, so it is interpreted with the person's prescriptions.
Medicines prescribed for psychiatric conditions and anxiety, identified by confirmation when a medication list needs to be checked.
Yes. 9-Hydroxyrisperidone is one of the 76 compounds in the LabX LC-MS/MS confirmation panel, reported as detected at or above 50 ng/mL. It is a breakdown product of risperidone (Risperdal). 9-Hydroxyrisperidone is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
LabX reports 9-Hydroxyrisperidone as detected at or above 50 ng/mL, and the method's reportable range is 50–4,000 ng/mL. A result below the cut-off is reported as not detected; it does not prove none was present.
The laboratory lists an approximate window of 1-5 days, but it varies with dose, frequency of use, metabolism and hydration, and cannot be used to tell when something was taken.
9-Hydroxyrisperidone is not one of the 12 lines on the LabX 12-panel screen. It is identified by adding laboratory confirmation, which tests for all 76 compounds on the panel.
As paliperidone, it is prescribed for schizophrenia and schizoaffective disorder, including as a long-acting injection.
9-Hydroxyrisperidone is a breakdown product of risperidone (Risperdal). Laboratories measure it because it shows the parent drug was actually processed by the body.
Terms on this page: metabolite · cut-off · detection window · presumptive result · confirmation test. More questions: LabX answers.
Test for 9-Hydroxyrisperidone and 75 other compounds
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